MGN ImageOLEAN – Two new cases of COVID-19 were reported in Cattaraugus County on Thursday morning.The Cattaraugus County Health Department says the 52nd case involves a female healthcare worker who received an antibody test that indicated she could have current infection.A COVID-19 test later revealed she was indeed positive for the virus. Prior to being tested the woman was asymptomatic.The 53rd COVID-19 case involves a male resident who was also asymptomatic. For the most part, health officials say, he denies any contact with a positive COVID-19 case. A contact tracing investigation is now underway for both new cases.There is now a total of 53 cases, with 14 active, 37 recovered and two deceased in Cattaraugus County. Share:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to email this to a friend (Opens in new window)
Researchers working as part of the University of Georgia’s Regenerative Bioscience Center have developed a new way to identify and sort stem cells that may one day allow clinicians to restore vision to people with damaged corneas using the patient’s own eye tissue. The UGA researchers published their findings in Biophysical Journal.The cornea is a transparent layer of tissue covering the front of the eye, and its health is maintained by a group of cells called limbal stem cells. When these cells are damaged by trauma or disease, the cornea loses its ability to self-repair.“Damage to the limbus, which is where the clear part of the eye meets the white part of the eye, can cause the cornea to break down very rapidly,” said James Lauderdale, the paper co-author and associate professor of cellular biology in UGA’s Franklin College of Arts and Sciences. “The only way to repair the cornea right now is to do a limbal cell transplant from donated tissue.”In their study, researchers used a new type of highly sensitive atomic force microscopy, or AFM, to analyze eye cell cultures. Created by Todd Sulchek, an associate professor of mechanical engineering at Georgia Tech, the technique allowed researchers to probe and exert force on individual cells to learn more about the cell’s overall health and its ability to turn into different types of mature cells.They found that limbal stem cells were softer and more pliable than other cells, meaning they could use this simple measure as a rapid and cost-effective way to identify cells from a patient’s own tissue that are suitable for transplantation.“Todd’s technology is unique in the tiniest and most sensitive detection to change,” said Lauderdale. “Just think about trying to gently dimple or prod the top of an individual cell without killing it; with conventional AFM it’s close to impossible.”Building on their findings related to cell softness, the research team also developed a microfluidic cell sorting device capable of filtering out specific cells from a tissue sample. With this device, the team can collect the patient’s own tissue, sort and culture the cells, and place them back into the patient – all in one day, said Lauderdale. It can take weeks to perform this task using conventional methods.The researchers are quick to caution that more tests must be done before this technique is used in human patients, but it may one day serve as a viable treatment for the more than 1 million Americans who lose their vision to damaged corneas every year. The group first started this research with the hope of helping children with aniridia, an inherited malformation of the eye that leads to breakdown of the cornea at an early age. Because aniridia affects only one in 60,000 children, few organizations are willing to commit the resources necessary to combat the disease, Lauderdale said.“Our first goal in working with such a rare disease was to help this small population of children, because we feel a close connection to all of them,” said Lauderdale, who has worked with aniridia patients for many years. “However, at the end of the day this technology could help hundreds of thousands of people, like the military, who are also interested in corneal damage, common in desert conditions.”Steven Stice, a Georgia Research Alliance Eminent Scholar, who plays an important role in fostering cross-interdisciplinary collaboration as director of the RBC, initially brought the researchers together and encouraged a seed grant application through the center for Regenerative Engineering and Medicine, or REM, a joint collaboration between Emory University, Georgia Tech and UGA.“A culture is developing around seed funding that is all about interdisciplinary collaboration, sharing of resources, and coming together to make things happen,” said Stice. “Government funding agencies place a high premium on combining skills and disciplines. We can no longer afford to work in an isolated laboratory using a singular approach.”The REM seed funding program is intended to stimulate new, unconventional collaborative research and requires equal partnership of faculty from two of the participating institutions.“We tend to get siloed experimentally,” says Lauderdale. “To a biologist like me, all cells are very different and all atomic force microscopes are the same. To an engineer like Todd it’s just the opposite.”The study, “Cellular Stiffness as a Novel Stemness Marker in the Corneal Limbus,” is available at www.cell.com/biophysj/fulltext/S0006-3495(16)30771-8. Funding was provided by an NIH NIGMS Biotechnology Training Grant on Cell and Tissue Engineering, the Knights Templar Eye Foundation, the Center for Regenerative Engineering and Medicine, the Sharon Stewart Aniridia Research Trust and the NSF CMMI division.
JRU improved to 2-8, while sending AMA to its fifth straight defeat and fall to a 1-8 card.Robbie Manalang showed the way for the Titans with 26 points and three assists, while Carlo Escalambre had 21 markers and eight boards.The Scores:JRU 98 — Porter 21, Apinan 17, Grospe 17, Pontejos 17, Yu 8, Mendoza 7, De Guzman 6, Dela Virgen 2, Silvarez 2, Esguerra 1, Bordon 0, Sawat 0.AMA ONLINE EDUCATION 87 — Manalang 26, C. Escalambre 21, Martinez 16, Andaya 7, Garcia 6, Paras 6, Lao 5, Antonares 0, Quijano 0, Taganas 0.ADVERTISEMENT Judy Ann’s 1st project for 2020 is giving her a ‘stomachache’ Kris Porter scattered 21 markers and six rebounds, while Ervin Grospe and Jeckster Apinan both tallied 17 points and five boards apiece.JRU coach Gio Lasquety commended his players for stepping up to the plate despite the team’s struggles this conference.FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkSPORTSTim Cone, Ginebra set their sights on elusive All-Filipino crown“It was evident that the team’s maturity wasn’t there during that eight-game losing skid. Bright side there is we’re learning and we’re gaining valuable lessons in this campaign,” he said.The Heavy Bombers didn’t shy away from seizing this opportunity in a battle between two also-ran squads, setting the tone and taking a 16-5 advantage to open the game before extending the lead to as high as 20, 59-39. Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew LATEST STORIES Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Scarlett Johansson, Sterling K. Brown among SAG Awards presenters Cabuyao City rising above the ashes through volunteerism Quarters: 28-13, 53-35, 77-66, 98-87.Sports Related Videospowered by AdSparcRead Next In Liverpool, Man United sees the pain and path to recovery Nadine Lustre’s phone stolen in Brazil Don’t miss out on the latest news and information. Jiro Manio arrested for stabbing man in Marikina PBA IMAGESJose Rizal University saved some semblance of pride after ending its eight-game losing skid with a 98-87 victory over AMA Online Education in the 2018 PBA D-League Aspirants’ Cup Monday at Ynares Sports Arena in Pasig.Paolo Pontejos made the big shots late for the Heavy Bombers as he dropped seven of his 17 points in the fourth quarter to fend off the Titans’ late rally that cut what was once a 20-point advantage down to just seven, 81-74 with 7:19 remaining.ADVERTISEMENT Pacquiao to fellow boxers, athletes: ‘Humble yourself’ Conor McGregor seeks to emerge from controversy in UFC comeback MOST READ Recto seeks to establish Taal rehab body to aid community, eruption victims View comments